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Yıldız Technical University

DEPARTMENT OF BIOENGINEERING
Projects

International Projects 

  1. Intensive Program: Sustainable Utilization of Renewable Resorces, Turkish Project Partner, 2009-2013.

  2. Development of multifunctional matrix structure for use in affinity biosensors liquid chromotography", TÜBİTAK, The Ministry of Ukraine for Education and Science, 2004-2006, MİSAG-UKR-1.


Projects funded by TÜBİTAK

  1. Development of a New Measurement Method Simultaneously Performing Short, Medium and Long Term Blood Sugar Measurements, 116S758, 2017.

  2. Development of Polymeric Diagnostic and Treatment Platforms with Controlled Polymerization and Bioorthogonal Methods, 214M175, 2015. 

  3. Production, Characterization and Adsorption Performance of a Novel Adsorbent with Additive, 115M469, 2015.

  4. Development of a Rapid Diagnostic Kit for Influenza A Infection with an Immunochromatography Method Based on M2e Specific IgY Antibody, 115S132, 2015.

  5.  Production of Bioactive Glass from Rica Husk Silica for using in Artificial Bone and Its Effects on Osteocytes, 213M647, 2014.

  6. Development and Protective Effects of Nanoparticle Vaccine Formulations for Visseral Leishmaniasis of L. Infantum, 213S148, 2014.

  7. Synthesis, Characterization and Evaluation of Small Molecule Storage Properties of Transition Metal-Containing Organic/Inorganic Hybrid Materials under Hydrothermal Conditions using Aromatic Organophosphonic Acid Bridge Ligands, 212T060, 2012-2015. 

  8. Development of a New Early Diagnosis Method for Myocardial Ischemia Using a Potentiometric Ion-Selective Sensor System, 112S166, 2012.

  9. Synthesis and Characterization of PVP-b-PEG (Polyvinylpyridine-B-Poly(ethylene glycol methyl ether methacrylate)) Copolymers as Potential DNA Carriers via the RAFT Method, 110T570, 2010–2011.

  10. A New Polymer-Based Approach for the Development of a Vaccine Against Leishmaniasis: Lipophosphoglycan (LPG)-Polymer Conjugates, 108S170, 2008–2011.

  11. Design, Synthesis, and Characterization of Polymeric Structures with Different Properties as Antisense Oligonucleotide Carriers, and Delivery of Antisense Oligonucleotides to Tumor Cells, 107T864, 2008–2010.

  12. Determination of the Three-Dimensional Structure of the Lactate Dehydrogenase Enzyme of Plasmodium vivax and Comparison of the Gene Encoding the Lactate Dehydrogenase Enzyme of Plasmodium with Those of Other Apicomplexan LDHs Using a Directed Mutagenesis Method, 104T215, 2005–2010

SAN-TEZ Projects
 
  1. Development of a Diagnostic Kit Based on Monoclonal Antibody Technology Against Lipophosphoglycan Molecules Isolated from L. tropica, the Causative Agent of Cutaneous Leishmaniasis, 0254.STZ.2013-2, 2014.
 
 
Istanbul Development Agency Projects
 
  1. Design of a New and Effective Microalgae Cultivation System Using Different Wastewater Sources and Biofuel Production, TR10/14/EVK/0002, 2014.
  2. Tulip Production in a Hydroponic System Using Biosensors in a Biotechnological Greenhouse, İSTKA/2012/BİL/332, 2013.
TAGEM Projects
 
  1. Optimization Studies and In Vitro Cell Tests for the Evaluation of Nanoporous Silica Aerogels Derived from Agricultural Waste as Food Additives, TAGEM-17/R&D/11, 2017.
  2. Development of Nanoscale Vaccine Formulations Against Toxoplasma gondii and Evaluation of Their Efficacy in Laboratory Animals, TAGEM-15ARGE-41, 2015.
  3. Use of Microalgal Exopolysaccharides in the Dairy Desserts Industry and Determination of Their Bioactive, Rheological, and Technological Properties, TAGEM-15ARGE-35, 2015.
  4. Investigation of the Inhibition Potential of Coumarin Derivatives on the Enolase Enzyme of Theileria annulata to Identify a New Drug Candidate for the Treatment of Theileriosis, TAGEM-14/ARGE/17, 2014.
  5. Development and Application of Selective Sensors for Calcium and Salicylic Acid for the Early Detection of Plant Diseases in Greenhouses, TAGEM-14/ARGE/05, 2014.
 
 
DPT Projects
 
  1. Biomedical Materials and Artificial Tissues, 25-DPT-07-04-01, 2005–2010.
  2. Production of Dental Restoration Materials, 24-DPT-07-04-01, 2004–2006.
  3. Development of Polymer-Peptide Conjugates for Vaccine Applications, 23-DPT-07-04-03, 2003–2006.
  4. Functional Biopolymer Systems, 23-DPT-07-04-02, 2003–2006.
  5. Establishment of Control Systems for the Identification of Transgenic Foods within the Scope of Biosafety, 23-DPT-07-04-01, 2003–2006.
YTU BAP Projects
 
  1. Development of a Graphene-Polycaprolactone (PCL)-Based 3-D Culture Model for the Use of Nasal-Derived Neural Stem Cells in Tissue Engineering, 2016-07-04-KAP01, 2016.
  2. Investigation of the Bioactivity, Ion Release, and Mechanical Properties of Resin-Based Dental Composites Prepared with the Addition of Aluminum-Doped Bioactive Glasses, 2016-07-04-GEP02, 2016.
  3. Microbial Biofertilizer with Controlled Release, 2016-07-04-GEP01, 2016.
  4. Synthesis and Characterization of Gelatin with Functional Properties, 2016-07-04-DOP06, 2016.
  5. Development and Structural Analysis of Conjugates of Synthetic Polymers with Lipopolysaccharides for the Creation of a Vaccine Model Against Q Fever, 2016-07-04-DOP05, 2016.
  6. Synthesis and Characterization of Synthetic Peptide-Polymer Conjugates and Naniformulations Targeting the Ebola Virus, 2016-07-04-DOP04, 2016.
  7. Development of New Potentiometric Electrodes Selective for Iron (II) and (III) Using Polyvinyl Chloride Membranes in a Composite Structure, 2016-07-04-DOP03, 2016.
  8. Investigation of Polymorphisms in Specific Genes Associated with Bronchopulmonary Dysplasia in the Turkish Population, 2016-07-04-DOP02, 2016.
  9. Production of Bioactive Glasses with Different Compositions Using the Biosilica Melting Method and Investigation of Their Bioactivity, 2016-07-04-DOP01, 2016.
  10. Investigation of the Antimicrobial and Antioxidant Effects of Macro- and Microalgae, 2016-07-04-YL13, 2016.
  11. Preparation of Bioactive Polymers for Use in Medical Diagnostic Applications, 2016-07-04-YL11, 2016.
  12. Development of Dextran-Coated Silica Aerogels as a Drug Delivery System for Colon Cancer Treatment, 2016-07-04-YL08, 2016.
  13. Investigation of the Cytotoxicity of Functional Polymers Used in Biomedical Applications, 2016-07-04-YL07, 2016.
  14. A Metal-Induced Oxidative Stress-Mediated Alzheimer’s Model in Human Neuroblastoma Cells, 2016-07-04-YL05, 2016.
  15. In Silico and In Vitro Applications of Drug Repurposing, 2016-07-04-YL04, 2016.
  16. Fabrication of Biophotovoltaic Cells Using Natural Pigments, 2016-07-04-YL03, 2016.
  17. Investigation of the Biogas Production Potential of Algae, 2016-07-04-YL01, 2016.
  18. Structural, Molecular, and Enzymatic Analyses of the Bos taurus Enolase Enzyme for Structure-Based Drug Design, 2015-07-04-KAP07, 2015.
  19. Design and Applications of Potentiometric Microsensor Arrays, 2015-07-04-KAP06, 2015.
  20. Investigation of the Interaction Between Mesenchymal Stem Cells Derived from Different Tissue Sources and Human Breast Cancer Cells, 2015-07-04-KAP04, 2015.
  21. Investigation of the Anti-Ulcer Effect of Okra (Abelmoschus esculentus L.) on Acute Gastric Mucosal Damage, 2015-07-04-KAP02, 2015.
  22. Development of Next-Generation Peptide Vaccine Models Against Ebola Virus Disease, 2015-07-04-KAP01, 2015.
  23. Production of Nanoporous Aerogels Using Biosilica Under Different pH, Acid, and Aging Conditions, and Investigation of Their Adsorption Performance in Sunflower Oil, 2015-07-04-KAP05, 2015.
  24. THE EFFECT OF FLUE GAS ON CHLORELLA MICROALGAE SPECIES AND THE USE OF THE PRODUCED MICROALGAE AS BIODIESEL, 2015-07-04-KAP03, 2015.
  25. Production of Parasite-Specific Immunoglobulin Y Antibodies for the Diagnosis of Toxoplasmosis, 2015-07-04-GEP03, 2015.
  26. Production of Hydrogels for Agricultural Applications, 2015-07-04-GEP02, 2015.
  27. Investigation of the Protective Efficacy Against Toxoplasmosis of a Combination of Toxoplasma Parasite Surface
  28. Protein and an Adjuvant-Effective Polymer, 2015-07-04-GEP01, 2015.
  29. Investigation of the Feasibility of Using a Calcium-Selective Sensor for the Detection of Plant Diseases, 2015-07-04-YL01, 2015.
  30. Production of Bioactive 45S5 Glasses Doped with Titanium and Biosilica via the Fusion Method, 2016-07-04-YL02, 2016.
  31. Removal of Certain Impurities from Sunflower Oil Using Nanoporous Aerogel, 2015-07-04-YL05, 2015.
  32. Production of Biosilicate 45S5 Bioactive Glasses Suitable for Use as Artificial Bone and Their Effect on Osteocyte Cells, 2015-07-04-YL04, 2015.
  33. Microalgae Production and Its Evaluation for Bioethanol Production, 2015-07-04-YL03, 2015.
  34. Investigation of the Efficacy of Natural and Chemical Solvents in the Removal of Pesticide Residues from Tomatoes, 2015-07-04-YL02, 2015.
  35. Simultaneous Determination of Monovalent Anions and Cations Using Miniature Column Ion ChromatographyPotentiometry, 2014-07-04-KAP04, 2014.
  36. The Effect of Nitric Oxide on Tumor Development in Human Lung Cancer, 2014-07-04-KAP03, 2014.
  37. Investigation of the Use of Hydrophobic Aerogels as Insulating Plaster in the Construction Industry, 2014-07-04-KAP02, 2014
  38. Production of Adsorbents from Various Raw Materials, Such as Biological Wastewater Treatment Sludge and Algae, 2014-07-04-KAP01, 2014.
  39. Synthesis, Characterization, and Evaluation of the In-vitro Antioxidant Activity of Quercetin-Loaded Nanoparticles, 2014-07-04-GEP03, 2014.
  40. Synthesis and Characterization of Poly(4-vinylpyridine)-g-Poly(ethylene glycol) Copolymers, 2014-07-04-GEP01, 2014.
  41. Production of Caffeic Acid Phenethyl Ester-Loaded Nanoparticles and Investigation of Their Antimicrobial Activities, 2014-07-04-GEP02, 2014.
  42. Biolysis of Chalcopyrite and Pyrite Minerals Using Acidophilic Bacteria, 2014-07-04-DOP03, 2014.
  43. Production of Zeolite from Wheat Bran Ash and Investigation of Its Adsorption Performance, 2014-07-04-DOP02, 2014.
  44. Determination of Genetic Susceptibility to Ankylosing Spondylitis in Our Population Using Mass Spectrometry, 2014-07-04-DOP01, 2014.
  45. New-Generation Protective Peptide Vaccine Models: Development of Bioconjugates of Rabies Virus Peptides with
  46. Various Adjuvants, 2014-07-04-YL05, 2014.
  47. Conducting Bioinformatics Analyses and Establishing a Mass Spectrometry-Based Panel for the Diagnosis of Common Bacterial Species, 2014-07-04-YL04, 2014.
  48. Preparation of a Macroporous Tissue Scaffold from Protein-Based Natural Polymers, 2014-07-04-YL03, 2014.
  49. Evaluation of Algae for Bioethanol Production, 2014-07-04-YL02, 2014.
  50. Synthesis and Structural Analysis of Synthetic Peptide-Polymer Conjugates That Can Be Used as Immunogens Against Brucella abortus in Veterinary Medicine, 2014-07-04-YL01, 2014.
  51. Synthesis of Smart Bio-Conjugated Polymeric Structures for Biomedical Applications, 2013-07-04-KAP05, 2013.
  52. Design of Biopolymer-Based Cryogel Tissue Scaffolds, 2013-07-04-KAP03, 2013.
  53. Microalgae Production and Its Evaluation for Biodiesel Production, 2013-07-04-KAP08, 2013.
  54. Development of Next-Generation Peptide Vaccine Models for Protection Against Viral Infections, 2013-07-04-KAP07, 2013.
  55. Production of Bioactive Glasses Containing Mg, Al, and Sr from Silica Derived from Rice Husk Ash and Their Effect on Osteocyte Cells, 2013-07-04-KAP06, 2013.
  56. In Vitro Investigation of the Thermal, Mechanical, Structural, and Spectral Properties of Bulk-Fill Resin Composites Polymerized with Different Light Sources, 2013-07-04-KAP04, 2013.
  57. Investigation of the Interaction of Mesenchymal Stem Cells Derived from Different Tissue Sources with Peptide Hydrogel (BD™ Puramatrix™) and Poly(e-caprolactone) Scaffolds, and Development of a 3-D Cell Culture Model for Use in Cartilage Tissue Engineering, 2013-07-04-KAP02, 2013.
  58. Magnet Design for Industrial and Healthcare Applications, 2013-07-04-KAP01, 2013.
  59. Development of Insulin-Controlled Drug Delivery Systems, 2013-07-04-GEP03, 2013.
  60. Synthesis of Bioactive Micro- and Nanogels, 2013-07-04-GEP01, 2013.
  61. Simultaneous Production of Plant Nutrients and Electrical Energy in a Microbial Fuel Cell, 2013-07-04-GEP02, 2013.
  62. Investigation of the In Vitro and In Vivo Antiparasitic Effects of Different Combinations Containing Nanoparticles Against the Causative Agents of Cutaneous Leishmaniasis and Development of New Approaches for the Treatment of the Disease, 2013-07-04-DOP02, 2013.
  63. Investigation of Ischemia-Modified Albumin, Oxidative Stress, and Antioxidant Enzyme Levels in Acute Myocardial Infarction, 2013-07-04-YL07, 2013.
  64. Establishment of a Continuous Culture of Helicobacter Pylori, the Primary Pathogen of Gastric Cancer; Isolation and Purification of the Urease Antigen; and Development of an ELISA Diagnostic Kit, 2012-07-04-KAP09, 2012.
  65. Development of Production Methods for Widely Consumed Vegetables, Fruits, and Ornamental Plants in Hydroponic Systems, 2012-07-04-KAP08, 2012.
  66. Synthesis and Characterization of Bimetallic Organic-Inorganic Hybrid Skeleton Structures from Selected Multidentate Phosphonic Acids, 2012-07-04-KAP07, 2012.
  67. Monitoring the Role of Micro- and Macronutrients in Plant Growth Using Chemical and Biosensors, 2012-07-04-KAP06, 2012–2013.
  68. Use of Creatine and Creatinine Biosensors as Detectors in a Flow-Injection Analysis System: Simultaneous Determination of Creatine and Creatinine in Biological Fluids, 2012-07-04-KAP05, 2012–2014.
  69. Synthesis of Metal-Organic Framework Structures in Combination with Transition Metals Using Multidentate Organoimine Ligands and Aromatic Phosphonic Acids, 2012-07-04-KAP04, 2013-04-02.
  70. Mathematical Modeling of Structural Changes Occurring During the Photopolymerization of Bis-GMA-Based Dental Composites, 2012-07-04-KAP03, 2012–2014.
  71. Isolation, Culture, and Characterization of Human Olfactory Stem Cells and Investigation of Their Effect on the Recovery of Damaged Facial Nerve Cells (in Rats), 2012-07-04-KAP02, 2012–2013.
  72. Development of Solid-Media Plant Growth Substrates Using a New Approach for Hydroponic Soilless Farming Systems, 2011-07-04-GEP05, 2011–2013.
  73. Production of Echinacea purpurea (L.) Moench (Echinacea), Foeniculum vulgare Miller (Fennel), and Matricaria recutita L. (Chamomile) and Optimization of Production Conditions, 2011-07-04-GEP03, 2011–2013.
  74. Production of Nitrogen by Microorganisms and Its Use in Plant Production, 2011-07-04-GEP02, 2011–2013.
  75. Extraction of Methyl Esters from Hazelnut Oil Using a New Method, 2011-07-04-GEP01, 2011–2013.
  76. Investigation of Certain Gene Polymorphisms Thought to Be Associated with Prostate Cancer in Turkish Patients, 2012-07-04-DOP02, 2012–2014.
  77. Use of Silica Powders Produced from Rice Husk Ash in Dental Composites, 2012-07-04-DOP01, 2012–2014.
  78. Synthesis of Synthetic Peptides with Antigenic Properties of Canine Parvovirus and Development of Their Bioconjugates, 2011-07-04-DOP01, 2011–2012.
  79. Production of Alpha-Amylase from Haloarcula Hispanica, an Archaeal Bacterium, 2012-07-04-YL03, 2012–2013.
  80. Isolation and Cloning of the Gene Encoding the Lactate Dehydrogenase Enzyme in Bacteroides fragilis, Reported to Be Associated with Colon Cancer, 2012-07-04-YL02, 2012–2013.
  81. Development of a Metal-Organic Framework-Based Sensor Molecule for Drug Delivery Applications, 2012-07-04-YL01, 2012–2013.
  82. Development of Cell Culture Models for Determining the Toxicity of Metallic Nanoparticles, 2011-07-04-KAP06, 2011.
  83. Preparation, Characterization, and Investigation of the Antibacterial Properties of Antibacterial, Double-Layer Wound Dressing Materials, 2011-07-04-KAP05, 2011.
  84. Production of Archaea-Derived α-Amylase and Cellulase Enzymes and Determination of Their Enzyme Activities, 2011-07-04-KAP04, 2011.
  85. Isolation of the gene encoding the enolase enzyme of Theileria annulata by intron removal, its expression, and analysis via directed mutagenesis, 2011-07-04-KAP03, 2011.
  86. Biotechnological Greenhouse, 2011-07-04-KAP02, 2011.
  87. Tulip Production Using Biosensors in a Hydroponic System for the First Time in Turkey, 2011-07-04-KAP01, 2011.
  88. Synthesis and Characterization of N-(2-Hydroxypropyl) Methacrylamide (HPMA)-Vinylpyridine (VP) Copolymer via the RAFT Method, 2011-07-04-YULAP03, 2011–2012.
  89. Purification and Analysis of the Lactate Dehydrogenase Enzyme from Plasmodium falciparum, 2010-07-04-YL01, 2010–2011.
  90. Optimization of the Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells into Hepatocytes, 2010-07-04-DOP01, 2010–2012.
  91. Conjugation of Synthetic Peptides That Induce Melanoma with Polyacrylic Acid and Its Copolymers, 29-07-04-DOP01, 2010–2011.
  92. Investigation and Development of the Antioxidant Properties of Chemically Modified Superoxide Dismutase (SOD) in Rats with Streptozotocin (STZ)-Induced Diabetes, 2010-07-04-GEP01, 2010–2012.
  93. Microwave-Assisted Synthesis and Characterization of Conjugates of a Biodegradable Natural Chitosan Polymer with Protein and Polyacrylic Acid, 29-07-04-GEP01, 2010–2012.
  94. Isolation and Cloning of the Gene Encoding Lactate Dehydrogenase from Certain Apicomplexa Parasites for Use in Drug Design Studies, 2010-07-04-KAP01, 2010–2011.
  95. Production of Synthetic Polymer-Peptide Conjugates, 29-07-04-ODAP01, 2010–2012.
  96. Investigation of Leishmania in Donor Blood Samples Obtained from Blood Centers in Istanbul Using New and Conventional Diagnostic Methods, 29-07-04-02, 2009–2011.
  97. Alcoholysis of Frying Oils Using the Microwave Method, 29-07-04-01, 2009–2010.
  98. Investigation of Polymerization Shrinkage During Light-Curing of Dental Composites Prepared Using Different Fillers, 29-07-04-03, 2009–2010.
  99. Production of Magnesium Silicate Used in Biodiesel Purification from Renewable Biomaterials, 29-07-04-YL05, 2009–2010.
  100. Identification of Recommendations for the Development of Food Safety and Biosafety Strategies for Turkish Consumers, 23-07-04-01, 2003–2005.
  101. Polysaccharide Conjugates of Alpha-Amylase and Horseradish Peroxidase Enzymes, 23-01-02-04, 2003–2006.
    Functional Polymer-Peptide Conjugates, 22-07-04-01, 2003–2006.
  102. Chemical Modification of Mucor miehei Rennet, 21-01-02-03, 2001–2004.

 

 

 

 

 

 

 

 

 

 

 

 

© Yıldız Technical University DEPARTMENT OF BIOENGINEERING. İstanbul, Türkiye.